Children with complex systematic disease involving multiple diagnosis who are on AAFs and have any of the following risk factors for developing bone disease:
|6 months after commencing AAF||If continuing on AAF review annually|
|Iron profile: full blood count & ferritin(8)||Yes||Yes|
|Bone profile: vitamin D, parathyroid hormone (PTH), phosphate, calcium, and alkaline, phosphate (ALP) (2,3,4,9)||Yes||Yes|
|Electrolytes: sodium, potassium, magnesium (9)||Yes||Yes|
Monitoring may be required earlier or more frequently where there is a clinical concern, or with children that are likely to have/with known unstable micronutrient profiles. Serum levels of micronutrients, particularly phosphorus, should be routinely monitored by clinicians when Neocate is used as a primary or sole source or nutrition for patients with complex systemic diseaseinvolving multiple diagnoses and intestinal disease, *especially in combination with tube feeding and/or a history of prematurity. Neocate** formulas are intended for use under medical supervision.
*A retrospective review identified case studies of patients on primary or sole source of nutrition with diagnoses covering multiple systems, including congenital gastrointestinal anomalies and GI surgeries (such as necrotizing enterocolitis, esophageal atresia, tracheoesophagael fistula); neurological conditions (such as seizures intraventricular hemorrhage, hydrocephalus); respiratory (lung disease, tracheostomy, aspiration); cardiac (congenital heart disease); and other systemic conditions, often in conjunction with tube feeding and/or a history of prematurity2.
**Neocate is an amino acid-based formula for the dietary management of cow’s milk allergy, multiple food protein allergies, and other conditions where an amino acid diet is recommended.
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