Infatrini Supports Catch Up Growth in Infants with Faltering Growth¹⁻³

Infatrini is a Food for Special Medical Purposes, designed to support the dietary management of disease-related malnutrition and growth failure in infants and young children.

With 25 years of trusted nutritional expertise, we are now excited to introduce our latest innovation - Infatrini with 2'-FL + scGOS / lcFOS prebiotics.

2’-FL is the most abundant  Human Milk Oligosaccharide (HMO) in breastmilk⁴

HMOs are integral in supporting the infant’s immune system⁵

Infatrini is the only high energy formula for infants with 2'-FL + scGOS / lcFOS Prebiotics

Over 25 years of Infatrini & Clinical Research in Infants with Faltering Growth

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Well-tolerated in infants with faltering growth6

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Meets increased nutritional needs of infants with faltering growth1-3,6-9

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Improved growth and clinical outcomes, even in the most critically ill children1-3

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Provides immune support10-15, 16-24¥, 25^, 26^, 27*

The addition of 2’-FL to Infatrini compliments scGOS/lcFOS prebiotics to provide immune support10-15, 16-24¥, 25^, 26^, 27*

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scGOS/lcFOS (9:1)

GOS/FOS stimulates growth of beneficial bacteria10

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Prebiotic effect10-15

Stimulate growth and activity of beneficial bacteria

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2'-FL

Inhibits pathogen adhesion16-18¥

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Blocking the route of infection19, 20¥

2'-FL blocks entry of pathogens

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scGOS/lcFOS (9:1)             & 2'-FL

 

 

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Direct effect in immune cells21-24^

Direct immunomodulatory effects at the cellular level (e.g. modulating dendritic cell maturation)

IMPORTANT NOTICE: Infatrini is a Food for Special Medical Purposes for the dietary management of disease-related malnutrition and growth failure in infants and young children. It must be used under medical supervision. Suitable as a sole source of nutrition for infants from birth and young children up to 18 months of age (or 9kg). Refer to label for details.

2’-FL: 2'-fucosyllactose

scGOS/ lcFOS: short chain galacto-oligosaccharides / long chain fructo-oligosaccharides

† MIMS UK & Ireland, May 2025.

‡ Infatrini was launched in 1999 (data on file).

¥ preclinical data;

^ study in healthy term infants recieving a formula with GOS only (control) or GOS plus either 0.2g/L or 1.0g/L 2'-FL and compared to a breastfed reference group;

*post hoc analysis of the control group and the 0.2g/L 2'-FL formula group from the Marriage et al. 2015 study.

– Product can be provided to patients upon the request of a Healthcare Professional. They are intended for the purpose of professional evaluation only.

  1. Scheeffer VA et al. 2020. JPEN.44(2):348-354.
  2. Eveleens RD et al. 2019. J Hum Nutr Diet. 32:3-10.
  3. Zhang H et al. 2019 Nurs Crit Care. 24(2):97-102
  4. Thurl S et al. Nutrition Reviews. 2017. 75(11);920–933
  5. Ayechu-Muruzabal V et al. 2018. Front Pediatr. 6:239. 
  6. Delsoglio M et al. JPGN Reports. 2024; 5(S1):S1207
  7. EFSA 2014
  8. Cui Y et al. 2018. J Parenter Enteral Nutr. 42:196-204.
  9. Hawkes JS et al. 2006. Eur J Clin Nutr. 60(2):254–264
  10. Knol J et al. Acta Paediatrica 2005. 94(S449);31-33.
  11. Moro G et al. J Pediatr Gastroenterol Nutr. 2002;34:291-5.
  12. Moro G et al. Arch Dis Child. 2006;91:814-9.
  13. Knol J et al. J Pediatr Gastroenterol Nutr 2003. 36;566
  14. Bruzzese E et al. J Pediatr Gastroenterol Nutr 2006. 42;E1-E11
  15. Arslanoglu S et al. J Nutr 2008. 138:1091-1095
  16. Ruiz-Palacios GM et al. J Biol Chem. 2003;278(16):14112-20.
  17. Yu ZT et al. J Nutr. 2016;146(10):1980-1990.
  18. Weichert S et al. Nutr Res. 2013;33(10):831-8.
  19. Newburg DS et al. Glycobiolo y. 2004 Mar;14(3):253-63.
  20. Morrow A et al. J Nutr. 2005 May;135(5):13047.
  21. Overbeek S et al. J Pediatr Gastroenterol Nutr. 2019;68(S1):N-O-008
  22. Vos AP et al. Int Immunopharmacol. 2006;6(8):1277-86.
  23. Xiao L et al. Immune Re ulation in Mice. J Nutr. 2019b;149(5):856-69.
  24. van den Elsen LWJ et al. Benef Microbes. 2019;10(3):279-291.
  25. Goehrin KC et al. J Nutr. 2016;146(12):2559–2566.
  26. Marria e BJ et al. J Pediatr Gastroenterol Nutr. 2015;61(6):649-58.
  27. Reverri EJ et al. Nutrients. 2018;10(10):1346. 

Accurate at the time of publication: May 2025.

 

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