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Introducing Peptisip Energy HP


Heavy on protein, light on the gut

Peptisip Energy HP is a high energy, high protein peptide-based Oral Nutritional Supplement (ONS). For the dietary management of disease related malnutrition in patients with impaired GI function.

Fortisip compact protein range shot

Malnutrition is common across many patient groups. Up to 45% of patients with GI disorders are at risk of malnutrition.1,2

Peptisip Energy HP Malnutrition Graph V2

Malnutrition is state of nutrition in which a deficiency of energy, protein, and other nutrients causes adverse effects on the body's size, composition and function resulting in poorer clinical outcomes.3

Why are patients with GI disorders at higher risk of malnutrition?

Patients with GI disorders can present with several symptoms such as diarrhoea, bloating, abdominal pain and vomiting4.

If symptoms are improperly managed, this may lead to:

Management of GI symptoms leads to

Nutritional support is vital for patients with GI disorders, as emphasised in several ESPEN guidelines.5,6

Tolerance to formulations containing whole protein and fats is often poor in patients with GI disorders.4,7 

In patients with GI disorders, when absorption and digestion of nutrients is impaired, peptide-based feeds have been shown to improve tolerance.4,7

breaking down peptide-based feeds

Watch this presentation 'Breaking Down Peptide-Based Feeds'

Watch Mary Phillips discuss peptide-based feeds and explain who, why, and when to use them at the Nutricia Study Day 2022.

Introducing Peptisip Energy HP: heavy on protein, light on the gut 

Designed to improve GI tolerance and increase nutritional intake in patients with impaired GI function.⁷


Peptisip Energy HP Profile 2022
* Medium chain triglycerides.
** Helps minimise electrolyte losses that occur in patients with GI intolerance symptoms.
† Helps meet Vitamin D requirements in patients with impaired GI function who are at risk of Vitamin D insufficiency and deficiency.
Peptisip Energy HP Suitability Profile
†† Lactose level below 300mg/kg
 ‡ Certified by the Halal Food Council of Europe.
‡‡ Nutricia has Kosher approval for this product.

The evidence behind Peptisip Energy HP7

Patient compliance to Peptisip Energy HP was 18% higher than with the prescribed baseline* ONS7. Increased compliance led to improved nutritional intake:7

Peptisip Energy HP Energy Protein intake
* Prior to commencing the study patients were taking a different oral nutritional supplement. 
** A p-value of ≤0.05 is statistically significant.


Peptisip Energy HP reduced the incidence and intensity of 7 out of 8 key GI symptoms.7

Peptisip Energy HP Symptom Improvements

The only exception was bloating.

† A p-value of ≤0.05 is statistically significant.

Want to see how Peptisip Energy HP performed in its clinical trial? 

Peptisip Energy HP has been studied7 in a variety of patients with complex conditions requiring a peptide-based ONS. Results from two of these patients have been collated and and presented as case studies, which can be accessed below:


Don't just take our word for it: see what patient's had to say about Peptisip Energy HP.7

Peptisip Energy HP Patient Quotes


Peptisip Energy HP was well accepted by trial participants7


± Product can be provided to patients upon the request of a healthcare professional. They are intended for the purpose of professional evaluation only
  1. Meijers J.M., Schol J.M., van Bokhorst-de van der Schueren M.A., et al. (2009) Malnutrition prevalence in The Netherlands: results of the annual Dutch national prevalence measurement of care problems. Br J Nutr., 101(3), pp. 417-23.
  2. Russell C. and Elia M. (2012) Nutrition screening survey in the UK and Republic of Ireland in 2011. Hospitals, care homes and mental health units [pdf]. BAPEN. Available from: bapen.org.uk/pdfs/nsw/nsw-2011-report [Accessed on: May 2022].
  3. Stratton R, Smith T, Gabe S. 2018 Managing malnutrition to improve lives and save money [pdf]. BAPEN. Available from: bapen.org.uk/pdfs/reports/mag/managing-malnutrition.pdf [Accessed: May 2022].
  4. Alexander D.D., Bylsma L.C., Elkayam L, et al. (2006) Nutritional and health benefits of semi elemental diets: A comprehensive summary of the literature. World J gastrointest Pharmacol Ther., 7(2), pp. 306-19.
  5. Forbes A., Eschere J., Herbuterne X. et al. (2017) ESPEN guidelines: Clinical nutrition in inflammatory bowel disease. Clin Nutr., 26(2), pp.321-47.
  6. Pironi L., Arends J., Bozzetti F., et al (2017) ESPEN guidelines on chronic intestinal failure in adults. Clin Nutr., 36(2), pp.247-307.
  7. Nutricia ACBS trial, data on file 2022.
  8. Arvanitakis M., Ockenga J., et al. (2020) ESPEN guidelines: Clinical nutrition in acute and chronic pancreatitis. Clin Nutr., 39(3), pp.612-631.

All products shown are Foods for Special Medical Purposes for the dietary management of disease related malnutrition in patients with malabsorption and/or maldigestion and must be used under medical supervision

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